| ICAO code | MDCS |
| Country | Dominican Republic |
| Type | Flight Information Region |
| Center | 18.20835, -70.00155 |
| Airports | 37 |
| NOTAM | Santo Domingo FIR NOTAMs |
| METARs | 0 |
| SIGMETs | 0 |
| Size | 172,443 km2 |
| Adjacent |
| ID | Name | IATA | METAR | City | Region | Type |
|---|---|---|---|---|---|---|
| DO-0003 | Barahona Heliport | Barahona | Barahona | Heliport | ||
| DO-0004 | Javo Beach Heliport | Samaná | Heliport | |||
| DO-0005 | Grand Sirenis Punta Cana Heliport | La Altagracia | Heliport | |||
| DO-0006 | Don Juan Helipad | Hato Mayor | Heliport | |||
| DO-0007 | Baigua Airport | Higuey | La Altagracia | Small airport | ||
| DO-0009 | Cibao International Airport | STI | Santiago | Santiago | Midsized airport | |
| MDAB | Arroyo Barril Airport | Arroyo Barril | Samaná | Small airport | ||
| MDAD | Azua Airport | Azua | Azua | Small airport | ||
| MDAN | Cotui Angelina Airport | Cotui Angelina | Duarte | Small airport | ||
| MDBA | Consuelo Batey Anita airport | Consuelo | Hato Mayor | Small airport | ||
| MDBC | La Romana Batey Cacata airport | La Romana | La Romana | Small airport | ||
| MDBE | La Romana Batey Lechuga Airport | La Romana | La Romana | Small airport | ||
| MDBH | Maria Montez International Airport | BRX | Barahona | Barahona | Midsized airport | |
| MDBL | Boca Chica Airport | Boca Chica | Santo Domingo | Closed | ||
| MDBM | San Pedro De Macoris Airport | San Pedro de Macoris | San Pedro de Macorís | Small airport | ||
| MDCR | Cabo Rojo Airport | CBJ | Cabo Rojo | Pedernales | Midsized airport | |
| MDCY | Samaná El Catey International Airport | AZS | Samana | Samaná | Midsized airport | |
| MDCZ | Constanza - Expedición 14 de Junio National Airport | COZ | Costanza | La Vega | Small airport | |
| MDDJ | Dajabon Airport | Dajabon | Dajabón | Small airport | ||
| MDER | El Ranchito Airport | La Vega | La Vega | Small airport | ||
| MDES | Peñuela / Esperanza Field | Valverde | Valverde | Small airport | ||
| MDHN | Juancho Enriquillo Airport | Barahona | Pedernales | Small airport | ||
| MDJB | La Isabela International Airport | JBQ | La Isabela | Santo Domingo | Midsized airport | |
| MDJI | Jimani Airport | Independencia | Small airport | |||
| MDLL | Los Llanos de Sabanatosa Airport | San Pedro de Macorís | Small airport | |||
| MDLM | Los Montones Airport | San Cristobal | Santo Domingo | Small airport | ||
| MDLR | Casa De Campo International Airport | LRM | La Romana | La Romana | Midsized airport | |
| MDMA | Magdalena Cuya Airport | La Romana | La Altagracia | Small airport | ||
| MDMC | Monte Cristi Airport | Monte Cristi | Monte Cristi | Small airport | ||
| MDPC | Punta Cana International Airport | PUJ | Punta Cana | La Altagracia | Large airport | |
| MDPM | Piloto Airport | Monte Cristi | Monte Cristi | Small airport | ||
| MDPP | Gregorio Luperon International Airport | POP | Puerto Plata | Puerto Plata | Midsized airport | |
| MDSA | San Juan De La Maguana Airport | San Juan de la Maguana | San Juan | Small airport | ||
| MDSD | Las Américas International Airport | SDQ | Santo Domingo | Santo Domingo | Large airport | |
| MDSI | San Isidro Air Base | San Isidro | Santo Domingo | Midsized airport | ||
| MDWO | Walterio Airport | Monte Cristi | Monte Cristi | Small airport | ||
| TSDM | Santo Domingo | Nacional | Unknown | |||
| DO-0008 | Santiago Municipal Airport | Santiago de los Caballeros | Santiago | Small airport | ||
| MDBG | Higuey Airport | Salvaleón de Higüey | La Altagracia | Small airport | ||
| MDPO | Samana El Portillo Airport | Las Terrenas | Samaná | Small airport | ||
| MDSB | Sabana De Mar Airport | Sabana de la Mar | Hato Mayor | Closed | ||
| MDSJ | San Juan Airport | San Juan de la Maguana | San Juan | Closed |